An overview on lipospheres

Authors

  • C.H. Sirisha Department of Pharmacy, Joginpally B.R. Pharmacy College, Moinabad, 501504
  • B. Chaitanya Department of Pharmaceutics, Joginpally B.R. Pharmacy College, Moinabad, 501504
  • Lakshmi Naganathan Department of Pharmacognosy, Joginpally B.R. Pharmacy College, Moinabad, 501504
  • J.V.C. Sharma Department of Pharmacognosy, Joginpally B.R. Pharmacy College, Moinabad, 501504

Keywords:

Lipid based Drug Delivery System, Lipospheres, Lipid carrier, Solid-Lipid nanoparticle

Abstract

Recent advances in pharmaceutical research focuses on new delivery systems utilizing new devices to achieve modification of delivery time, targeting, as well as improve the in-vivo solubility and hence bioavailability of poorly soluble drugs. Lipospheres are amongst the promising particulate drug delivery systems for improving dissolution of water insoluble drugs. They were initially reported as particulate dispersion of solid spherical particles between 0.2 100μm in diameter consisting of solid hydrophobic fat core such as triglycerides or fatty acids derivatives, stabilized by mono layer of phospholipids. Lipid based drug delivery system (LDDS) or lipospheres are extensively employed as oral delivery systems for drugs and other active ingredients in the field of pharmaceutical, food, agriculture and cosmetic technology. This article presents various aspects of lipospheres like its types, formulation, techniques employed in preparation, evaluation techniques and applications.

Downloads

Published

2020-01-02

How to Cite

C.H. Sirisha, B. Chaitanya, Lakshmi Naganathan, & J.V.C. Sharma. (2020). An overview on lipospheres. World Journal of Pharmaceutical Sciences, 8(1), 6–12. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/139

Issue

Section

Review Article

Most read articles by the same author(s)