Dietary Antioxidants: True Fighters against Oxidative Stress Induced Cancer

Abstract

Abnormal activation or silencing of mitogen activated protein kinase (MAPK) pathways, protein kinase C (PKC) and phosphatidyl inositol -3- kinase (PI3k) result in uncontrollable cell growth which leads to translation of normal cells to cancer cells. Many phytochemical chemo preventive agents are capable of controlling these enzymes and preventing abnormal cell growth and proliferation. Diets rich in fruits and vegetables are gaining increased importance due to their significant role in reducing the risk of degenerative diseases such as cancer, cardiovascular diseases and other chronic diseases. This review summarize current information on different groups of dietary antioxidants and their possible role in chemo-prevention of most important human cancers.