Estimation of Metformin Hydrochloride by UV Spectrophotometric Method in Pharmaceutical Formulation

Authors

  • Ambadas R. Rote M.G.V’s Pharmacy College, Mumbai-Agra Road, Panchavati, Nashik (Pune University), Maharashtra, India
  • Ravindranath B. Saudagar KCT’s, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra, India

Keywords:

Metformin hydrochloride, UV Spectrophotometric, Estimation

Abstract

A simple and sensitive UV spectrophotometric method has been developed and validated for the estimation of metformin hydrochloride in tablet formulation. Metformin hydrochloride is determined spectrophotometrically at 232 nm using distilled water as solvent. It obeyed Beer's law in the range of 2-10 μg/ml. Percentage recovery of the drug for the proposed method ranged from 102-105% indicating no interference of the tablet excipients. The proposed method was found to be accurate and precise for routine estimation of metformin hydrochloride in bulk and pharmaceutical formulation.

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Published

2014-12-01

How to Cite

Ambadas R. Rote, & Ravindranath B. Saudagar. (2014). Estimation of Metformin Hydrochloride by UV Spectrophotometric Method in Pharmaceutical Formulation. World Journal of Pharmaceutical Sciences, 2(12), 1841–1845. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/estimation-metformin-uv-spectrophotometric-method

Issue

World J Pharm Sci 2014; 2(12): 1592-1990

Section

Research Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.