Extraction and primary characterization of water soluble contents from Pumpkin Fruit
Keywords:Dispersion, Drug carrier, Natural excipients, Pumpkin fruit, Solubility, Wettability
The use of natural herbs as excipients in pharmaceutical dosage form helps in preparing effective dosage form. The main objective of present study is extraction and characterization of water soluble contents from pumpkin fruit. In the present investigation the water soluble contents from pumpkin fruit was extracted. The hot water extraction method was used. Pumpkin fruits accumulate soluble carbohydrate; hence the product was found water soluble polysaccharides. The water soluble contents were characterized by Fourier transform infrared spectroscopy, X-ray diffractometry and Differential scanning calorimetric studies. High swelling index and low viscosity indicates the high wetting and dispersion properties. Hence it can be concluded that, natural, biodegradable and eco-friendly water soluble product of desired properties obtained from pumpkin fruit is novel approach in solubility enhancement of poorly water soluble drug.
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