Comparative study of natural disintegrants, selection criteria for superdisintegrants

https://doi.org/10.54037/WJPS.2022.100503

Abstract

Natural super disintegrants have been used for fast dissolving tablets because they are biodegradable, chemically inert, non-harmful, more affordable and widely available. The natural polymer improves the properties of the tablet as it is commonly used as diluents and binders. Super explosives are those substances that promote rapid decomposition in a lesser amount compared to explosives. Super disintegrants are the vehicles added to the tablet formulation to promote the breakdown of tablets and capsules into small microparticles in aqueous media, leading to an increase in surface area and promoting rapid drug release. Some research is going to develop safe and effective medication with super disintegrating agents that can be dissolved rapidly to treat the disease.