Synthesis, docking and anti-oxidant activity of Zn (II) complexes of oximes

Authors

  • Varadarassou Mouttaya Mounnissamy College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences(MTPG&RIHS), Indira Nagar, Gorimedu, Puducherry-605 006, India
  • Jarina Abdul College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences(MTPG&RIHS), Indira Nagar, Gorimedu, Puducherry-605 006, India
  • Ezhilarasi Gangatharan College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences(MTPG&RIHS), Indira Nagar, Gorimedu, Puducherry-605 006, India

Keywords:

Synthesis, Transition metal complex, Oximes, Antioxidant, DPPH assay, docking

Abstract

Zinc complexes have been prepared by reacting metal chloride with ortho chlorobenzaldehyde oxime, para dimethyl aminobenzaldehyde oxime and Vanillin oxime. Docking study has been carried out for prepared complexes by using autodock software against Biotin Carboxylase (3JZI) as a target protein. The antioxidant activity have been studied and compared with their ligands against ascorbic acid as standard by DPPH assay method which gave significant results of activity.

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Published

2015-08-01

How to Cite

Varadarassou Mouttaya Mounnissamy, Jarina Abdul, & Ezhilarasi Gangatharan. (2015). Synthesis, docking and anti-oxidant activity of Zn (II) complexes of oximes. World Journal of Pharmaceutical Sciences, 3(8), 1650–1660. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/synthesis-docking-antioxidant-zinc-complexes-oximes

Issue

World J Pharm Sci 2015; 3(8): 1471-1746

Section

Research Article

License

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