Cytotoxic Studies on Selected Siddha Plants

R. Ganesan; Mathuram Venkatanarasimhan; P. Elankani; R. Shakila; Ponniahsamy

Cytotoxic Studies on Selected Siddha Plants

Authors

R. Ganesan Siddha Central Research Institute, Arumbakkam, Chennai.
Mathuram Venkatanarasimhan Department of Chemistry, CSMDRIA, Arumbakkam, Chennai, India
P. Elankani Siddha Central Research Institute, Arumbakkam, Chennai.
R. Shakila Siddha Central Research Institute, Arumbakkam, Chennai.
Ponniahsamy Siddha Central Research Institute, Arumbakkam, Chennai.

Keywords:

Cytotoxic study, Andrographis echioides, Ocimum tenuiflorum, Barleria prionitis, Coldenia procumbens and Adriamycin (ADA)

Abstract

The methanolic extract of whole plant of Andrographis echioides (L.) Nees, Ocimum tenuiflorum L., Barleria prionitis L., Coldenia procumbens L. and chloroform extract of Coldenia procumbens L. were studied for the anticancer activity of the Human Ovarian Cancer Cell Line Ovkar -3 and Human Renal Cancer Cell Line 786-O in different concentrations (10,20,40 80 µg/ml) along with standard drug Adriamycin (Doxorubicin)(ADA)( Positive control compound).The results showed that all the extracts were non-cytotoxic at the dose levels studied and all of them showed activities of GI50 only at concentration > 80 µg/ml.

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Published

2015-09-17

How to Cite

R. Ganesan, Mathuram Venkatanarasimhan, P. Elankani, R. Shakila, & Ponniahsamy. (2015). Cytotoxic Studies on Selected Siddha Plants. World Journal of Pharmaceutical Sciences, 3(9), 1872–1876. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/cytotoxic-studies-selected-siddha-plants