A review on orally disintegrating tablet: As a new potential approaches for drug delivery system

Abstract

In the current scenario, orally disintegrating tablet are gaining more prominence as a novel potential drug delivery system & emerges as one of the popular & widely accepted dosage forms, especially for pediatric due to it troubleshoots the problem of dysphagia and geriatric patients suffering from Parkinson’s disorder or hand tremors. An orally disintegrating tablet is a drug dosage form available for imitated amount of the over the counter (OTC) and prescription medication. Over the past three decades, orally disintegrating tablets (ODTs) have gained substantial popularity as a preferable alternative to traditional tablets and capsules due to improved patient compliance. ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, typically in a matter of seconds, when placed on the tongue. It has been developed for oral administration, also called as fast-melt, rapid-melt, porous tablet or fast disintegrating tablet (FDTs). This article focuses on the patented technologist available and the advance made so far in the field of fabrication of orally disintegrating table. Apart from that this article also provide the detail information of need for development of ODT’s, formulation challenges and desired characteristics of orally disintegrating tablet, ingredient to be used in formulation of ODT’s, mechanism of tablet disintegration and evaluation.