Study of the role of some Scutellaria Iscandaria L. extract’s flavonoids on nanosilver synthesis

Authors

  • M.G. Ismailova Tashkent Pharmaceutical Institute, Aybek Street, Tashkent 100015, Uzbekistan
  • I.B. Shermatova Tashkent Pharmaceutical Institute, Aybek Street, Tashkent 100015, Uzbekistan
  • P.L. Ismailova Uzbek Scientific Research Chemical-Pharmaceutical Institute named after A. Sultanov, Aybek Street, Tashkent 100015, Uzbekistan
  • U.J. Ishimov Institute of Bioorganics, Aybek Street, Tashkent 100015, Uzbekistan

Keywords:

Silver nanoparticles, ScutellariaIscandaria L. extract, Green synthesis, Atomic Weight microscopies (АWМ), HPLC, Luteolin, Apegenin, Quersetin, Rutin

Abstract

Silver nanoparticles are synthesized with the method of “Green synthesis” using Scutellaria Isсandaria extract. The synthesized silver nanoparticles were studied by HPLS and Atomic Weight microscopies (AWM). Silver nanoparticles, like other nanoparticles, are characterized by unique properties associated with a high ratio of their surface to volume, which determines the high efficiency of their action. Much attention is paid to the functional activity of silver nanoparticles in terms of imparting both bactericidal and bacteriostatic properties to various materials and products. Firstly, this will allow a hundred-fold decrease in the metal concentration while maintaining all its bactericidal properties, and secondly, due to the large specific surface of the nanoparticles, the contact area of ​​silver with bacteria or viruses increases, significantly improving its bactericidal action [1]. In accordance with the results of the analysis, the content of flavonoids in the suspension samples with silver nanoparticles shows the complete absence of apigenin and quercetin, and the peaks characterizing Luteolin (-4.3 min), Rutin (-2.6 minutes) remain, although their content decreased to reading 0 , 05 mg / g and 0.0044 mg / g, respectively. The high activity of flavonoids such as luteolin, apegenin, quercetin and rutin has been proven. Therefore, Scutellaria Iscandaria L. can be a promising raw material for the synthesis of silver nanoparticles.

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Published

2020-02-01

How to Cite

M.G. Ismailova, I.B. Shermatova, P.L. Ismailova, & U.J. Ishimov. (2020). Study of the role of some Scutellaria Iscandaria L. extract’s flavonoids on nanosilver synthesis. World Journal of Pharmaceutical Sciences, 8(2), 19–25. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/141

Issue

Section

Research Article