CASSIA AURICULATA: A COMPREHENSIVE REVIEW OF THE NUTRITIONAL, EXPLORING SERUM LIPID PROFILE IN PATIENTS DIAGNOSED WITH MYOCARDIAL INFARCTION AT HAYAT ABAD MEDICAL COMPLEX PESHAWAR

Abstract

Myocardial Infarction (MI) is a critical medical emergency necessitating early diagnosis for effective patient management and complication prevention. Blood biomarkers serve a pivotal role in predicting and preventing MI. This study, conducted in the cardiology department at Hayatabad Medical Complex, Peshawar, focused on investigating the serum lipid profile in MI patients. Using a non-probability convenient sampling technique, 109 diagnosed MI patients were recruited, and 3 to 5 ml blood samples were aseptically collected and processed at the tertiary healthcare hospital. The collected samples were centrifuged to obtain serum, and routine biochemistry analysis using a COBAS analyzer was employed to measure serum lipid levels, including cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL-C), and very low-density lipoprotein (VLDL-C).Statistical analysis revealed a male predominance (63.3% vs. 36.7%), with the age group of 51 to 60 years being commonly affected (29%). Dyslipidemia analysis indicated a prevalent abnormal elevation of VLDL-C in 57.8% of MI patients, accompanied by hypertriglyceridemia in 33.9%. Additionally, 46.8% of patients exhibited a significant decrease in HDL levels, while 11.9% showed elevated LDL cholesterol and 2.8% presented with hypercholesterolemia. In conclusion, this study highlights that abnormal increases in blood lipid levels contribute to the predisposition of patients to myocardial infarction. The identification of elevated blood lipids underscores the need for immediate management to mitigate further complications in MI patients