ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF REMOGLIFLOZIN AND TENELIGLIPTIN IN PHARMACEUTICAL DOSAGE FORMS BY HPLC
Keywords:
Remogliflozin, Teneligliptin, Rp Hplc, Validation.Abstract
Remogliflozin and Teneligliptin was estimated with HPLC in a tablet dosage form, it was processed with Discovery C 18 column of dimensions 150 x 4.6 mm and 5μm. ammonium acetate and Acetonitrile was used as MP in it with a ratio of 65:35. Wavelength was identified at 210 nm. Rt of Remogliflozin and Teneligliptin was found at 2.206 and 2.646 min. %RSD of the drugs found at 0.6 % and 0.6%, with that the regression of both was seen at y = 52765x + 1014.4 and y = 73315x + 624.91 respectively, and the mean recovery was 99.70% and 99.93%. All the other paraments were validated and were observed within the limits.
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