ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF REMOGLIFLOZIN AND TENELIGLIPTIN IN PHARMACEUTICAL DOSAGE FORMS BY HPLC

Authors

  • Gogikar Pooja M. Pharmacy, Department of Pharmaceutical Analysis, Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad, Hyderabad, 500100, Medchal District.

Keywords:

Remogliflozin, Teneligliptin, Rp Hplc, Validation.

Abstract

Remogliflozin and Teneligliptin was estimated with HPLC in a tablet dosage form, it was processed with Discovery C 18 column of dimensions 150 x 4.6 mm and 5μm. ammonium acetate and Acetonitrile was used as MP in it with a ratio of 65:35. Wavelength was identified at 210 nm. Rt of Remogliflozin and Teneligliptin was found at 2.206 and 2.646 min. %RSD of the drugs found at 0.6 % and 0.6%, with that the regression of both was seen at y = 52765x + 1014.4 and y = 73315x + 624.91 respectively, and the mean recovery was 99.70% and 99.93%. All the other paraments were validated and were observed within the limits.

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Published

2024-12-26

How to Cite

Gogikar Pooja. (2024). ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF REMOGLIFLOZIN AND TENELIGLIPTIN IN PHARMACEUTICAL DOSAGE FORMS BY HPLC. World Journal of Pharmaceutical Sciences, 13(01). Retrieved from https://wjpsonline.com/index.php/wjps/article/view/1706

Issue

Section

Research Article