A short review on clinical trials in drug development

Abstract

Clinical trials are a set of tests in medical research and drug development that generate safety and efficacy data for health interventions in human beings. Clinical trial may occur in several different phases where the drugs are developed in several different phases to meet the multiple objectives in the safest, most efficient manner. The results from these trials are translated in the humans in a cautious manner that form the basis of clinical pharmacology which deals with Drug input, Pharmacokinetics, Pharmacodynamics, Pharmacogenetics, Pharmacogenomics, Factors affecting Drug response and finally the toxicity and side effects. This article describes the phases of clinical trials & clinical drug development process.