A REVIEW ON ANALYTICAL CHROMATOGRAPHIC METHODS FOR ESTIMATION OF CETILISTAT IN PHARMACEUTICAL FORMULATION AND BULK FORM

Authors

  • Miss. Vrushali M. Pawar Research scholar, Department of Pharmaceutical Chemistry, Sahyadri College of Pharmacy, Methawde, Sangola, Dist- Solapur, Maharashtra, India.

Keywords:

Cetilistat, Lipase-Inhibitor, High performance liquid Chromotography, Uv-Spectroscopy.

Abstract

Overweight and obesity pose serious health concerns to both individuals and society. Obesity causes a number of physiological, psychological, and social difficulties in addition to visual impairments and abnormal physiological metabolism, Obesity is associated with the development of numerous chronic diseases and is a major risk factor for a number of illnesses, such as diabetes, hypertension, hyperlipemia, cardiovascular disease, and even cancer. Compared to those of normal weight, obese people are more prone to suffer type 2 diabetes, gallbladder disease, and syndrome. Gout, osteoarthritis, hypertension, and coronary heart disease all increase the risk of obesity, and they may also have some effects on reproduction. Pancreatic lipase inhibitors are crucial for the metabolism of fat in humans. This article discusses the many processes needed to develop and validate an HPLC analysis and UV technique. Testing for accuracy, specificity, linearity, range, limit of detection, limit of quantification, robustness, and system adaptability are all part of the ICH Guidelines' validation of an HPLC process. In light of this, the purpose of this review is to present a summary and analysis of HPLC techniques that have been documented in the literature for the estimate of cetilistat in pharmaceutical dosage forms, either alone or in combination. The comparative application of HPLC by UV/PDA techniques for Cetilistat estimation is covered in the review that follows. Future analytical research needs can be adequately met by Cetilistat using the current compilation.

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Published

2025-07-03

How to Cite

Miss. Vrushali M. Pawar. (2025). A REVIEW ON ANALYTICAL CHROMATOGRAPHIC METHODS FOR ESTIMATION OF CETILISTAT IN PHARMACEUTICAL FORMULATION AND BULK FORM. World Journal of Pharmaceutical Sciences, 13(02). Retrieved from https://wjpsonline.com/index.php/wjps/article/view/1871

Issue

Section

Review Article