Serum uric acid levels and its association with type 2 diabetes mellitus

Dr Sanjeev Kumar; Dr Pallavi Mahajan; Dr Ashima Badyal

Authors

Dr Sanjeev Kumar Assisatnt Professor, Department of Medicine, GMC, Kathua, J&K
Dr Pallavi Mahajan Assistant Professor, Department of Biochemistry Acharya Shri Chander College of Medical Sciences and Hospital
Dr Ashima Badyal Lecturer, Department of Biochemistry, GMC, Jammu, J&K

Keywords:

T2DM, Metabolic syndrome, Uric acid, Diabetic patients

Abstract

Diabetes Mellitus is characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism. Elevated uric acid levels are often found in individuals with the metabolic syndrome. A prospective study was conducted on 400 type 2 diabetic patients attending the Medicine OPD (Sub District Hospital Hiranagar) from July- December 2018, with the aim to find correlation between uric acid and glycemic status in type2 DM. Patients of type 2 DM were diagnosed as fasting plasma glucose ≥ 126mg/dl and 2 hrs post prandial glucose ≥ 200mg/dl. Among the male patients, 46.8% were above 60 years of age group and only 6.9% in the age of 30-39 years as compared to females having relative percentage of 44.5 & 7.1 in the respective age groups. The SUA concentration rose with increasing fasting plasma levels up to the level of 140 mg/dl, but decreased thereafter. It was observed that Uric Acid was positively related to BMI and inversely related to HbA1c, FBS and RBS. Since HbA1c, FBS and RBS are typically taken to be diagnostic criteria for T2DM, Serum Uric Acid (SUA) might act as predictor and marker of T2DM but its clinical implications need to be studied further.