Anti-neoplastic activities of targeted bio- moieties of Dodonaea Viscosa

A.M. Krupanidhi; Prakash Dabadi; Jayamma Kulkarni; Darshan Ekbote; Prasd Davan

Anti-neoplastic activities of targeted bio- moieties of Dodonaea Viscosa

Authors

A.M. Krupanidhi Bapuji Pharmacy College, Davangere-577004, Karnataka, India
Prakash Dabadi Bapuji Pharmacy College, Davangere-577004, Karnataka, India
Jayamma Kulkarni Bapuji Pharmacy College, Davangere-577004, Karnataka, India
Darshan Ekbote Bapuji Pharmacy College, Davangere-577004, Karnataka, India
Prasd Davan Bapuji Pharmacy College, Davangere-577004, Karnataka, India

Keywords:

SCFC, EAC, Dodonaeaviscose, DPPH, SOD

Abstract

The objective of the present study was focused phytochemical screening of Dodonia viscosa (DV) Versatile medicinal plant. The arial parts of DV was subjected to the super critical fluid extraction (SCFE) and confirmed for the presence of many phytoconstituents like flavonoids, glycosides, saponins etc. Further the procured extract was subjected to column chromatography and isolated the active bio-compounds, those were subjected for antioxidant activity by following DPPH and SOD method. Antineoplastic activity was carried out against Erlichs Ascites Carcinoma (EAC)-induced mice. The extract and isolated bio compound showed good antioxidant and anticancer activity, however further investigations of MTT-assay is required for structural elucidation of bioactive compounds.

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Published

2018-09-30

How to Cite

A.M. Krupanidhi, Prakash Dabadi, Jayamma Kulkarni, Darshan Ekbote, & Prasd Davan. (2018). Anti-neoplastic activities of targeted bio- moieties of Dodonaea Viscosa. World Journal of Pharmaceutical Sciences, 6(10), 5–13. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/anti-neoplastic-targeted-bio-moieties-dodonaea-viscosa