Anti-inflammatory, Antimicrobial and Cytotoxic Activities of Essential Oil Extracted from Salvia officinalis L.

C. Sivaraj; Nikhishaa Sree R; P. Arumugam; K. Gayathri

Anti-inflammatory, Antimicrobial and Cytotoxic Activities of Essential Oil Extracted from Salvia officinalis L.

Authors

C. Sivaraj Department of Natural Products, Armats Biotek Training Research Institute, Chennai- 600032.
Nikhishaa Sree R Department of Biotechnology, Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai-600067.
P. Arumugam Department of Natural Products, Armats Biotek Training Research Institute, Chennai- 600032.
K. Gayathri Department of Biotechnology, Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai-600067.

Keywords:

Salvia officinalis, phenolic compounds, antimicrobial, antiinflammatory, HeLa, MTT

Abstract

The aim of the study was to evaluate antimicrobial, antiinflammatory and cytotoxic activities of essential oil extracted from Salvia officinalis using chloroform as the solvent by Soxhlet apparatus. Total phenols and flavonoids were estimated by Folin-Ciocalteu reagent and AlCl₃ reagent methods. The antimicrobial activity was carried out by well diffusion method while the antiinflammatory activity was performed by albumin as well as BSA denaturation inhibition assay method. The cytotoxic activity was carried out on HeLa cell lines by MTT assay method.

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Published

2017-05-27

How to Cite

C. Sivaraj, Nikhishaa Sree R, P. Arumugam, & K. Gayathri. (2017). Anti-inflammatory, Antimicrobial and Cytotoxic Activities of Essential Oil Extracted from Salvia officinalis L. World Journal of Pharmaceutical Sciences, 5(6), 257–263. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/anti-inflammatory-antimicrobial-salvia-officinalis