Drug utilization pattern in patients suffering from type 2 diabetes mellitus visiting medicine department of MMIMSR and the most commonly used anti diabetic drugs

Abstract

Diabetes mellitus is a condition characterized by chronic hyperglycemia with disturbances of carbohydrate, protein and fat metabolism. This prospective observational study determined the utilization pattern of anti-diabetic drugs and the most commonly used anti-diabetic drug/drugs (with or without insulin) on patients suffering from type 2 diabetes mellitus (newly diagnosed as well as on treatment) attending the Medicine department of MMIMSR, Mullana, Ambala. A total number of 200 patients suffering from type 2 diabetes completed this study of 3 months duration. Utilization pattern of various anti diabetic drugs was determined on the basis of their ability to achieve glycemic targets, measured through the investigations like the fasting blood glucose, postprandial blood glucose (assessed on baseline, 6 weeks, 12 weeks) and HbA1c (assessed on baseline and 12 weeks). The primary end point was mean change in HbA1c from baseline to week 12. Safety was assessed by incidence of hypoglycemia and other adverse events. There was significant reduction in HbA1c, FBS, PPBS levels from baseline to 12 weeks and the p value obtained was highly significant. In conclusion, this study revealed that the combination of metformin and insulin was the most commonly prescribed drugs in type 2 diabetes patients.