Antibiogram of Salmonella serotypes at a tertiary care hospital in North India

Abstract

Enteric fever is a world-wide problem caused by Samonella enterica serotype Typhi or Paratyphi A/B. A considerable variation has been found in the incidence of antibiotic resistance among salmonellae reported from different parts of India. A total of 11059 blood cultures were received in the Department of Microbiology. All the samples were processed by standard microbiological procedures. Antimicrobial susceptibility testing was done following Kirby and Bauer disc diffusion method in accordance with Clinical and Laboratory Standards Institute (CLSI). A total of 51 salmonella serotypes were isolated, out of which 40 (78.4%) were S.Typhi and 11(21.6%) were S.Paratyphi A. Most effective antibiotics were chloramphenicol and cefepime. The changing antibiogram demands appropriate antibiotic sensitivity testing, good choice, proper dosage, proper duration of therapy and rational prescribing of antibiotics in a particular geographical region.