A Study on effect of Oxidative Stress in Senile Cataract

Abstract

As antioxidants play a protective role in the pathophysiology of age related diseases, understanding the physiological status of antioxidant concentration among people at high risk for developing senile cataract is of interest. In the present study 100 cases of senile cataract were taken and compared with 100 healthy age matched controls. Plasma levels of Vitamin E, Vitamin C and Superoxide dismutase between cataract cases and control groups were found to be statistically significant(P<0.001). The present study suggests that if educational and social instructions can be popularized regarding the beneficial effects of vitamins and nutritional status of food that we eat, we can make the right decision to prevent or delay the initiation of cataract formation. It also throws a light on the probability that low level of antioxidants and increased oxidative stress may have a role to play in the etiopathogenesis of senile cataract.