A short review on liquisolid technology in anti-fungal drugs

https://doi.org/10.54037/WJPS.2022.100116

Abstract

This article is based on the mode of action of antifungals and their mechanisms of action and approach for the treatment of fungal diseases like Aspergillosis, Candidemia, Fusariosis, and coccidioidomycosis. There are many different types of mechanisms contribute to the development of resistance to antifungals. The mechanisms include alteration in the drug target, sterol biosynthesis, the reduction in the intercellular concentration of target enzyme, and to make too many copies of the substance of the antifungal drug target.