Evaluation of Antioxidant and Antidiabetic Activity of Menthaarvensis Linn.

Abstract

The anti-diabetic activity of ethanol (70%) extract of Menthaarvensis was performed on in vivo model along with antioxidant activity and determination of total polyphenol content. Ethanol extract of Menthaarvensis contains 4.7% of total extractable polyphenols. The antioxidant activity studied on ethanol extract showed very promising result in superoxide radical, hydroxy radical and DPPH radical methods. The antioxidant activity is directly correlated to the anti-diabetic activity of drug. The in vivo anti-diabetic activity of ethanol extract of Menthaarvensis was performed on streptozotocin-induced diabetes mellitus showed significant inhibition of blood glucose level as compared to control and similar to that of standard glibenclamide. The overall data potentiates the traditional value of Menthaarvensis as an anti-diabetic drug.