Comparative study of atorvastatin, metformin and telmisartan on high fat induced obesity in Albino Wistar rats: DOI: https://doi.org/10.54037/WJPS.2021.9905

C. Jothimanivannan; M. Vanitha; V. Sasikumar; T. Sampathkumar

Comparative study of atorvastatin, metformin and telmisartan on high fat induced obesity in Albino Wistar rats

DOI: https://doi.org/10.54037/WJPS.2021.9905

Authors

C. Jothimanivannan Department of Pharmaceutical Chemistry, SS Institute of Pharmacy, Sankari, Salem – 637301
M. Vanitha Department of Pharmacology, SS Institute of Pharmacy, Sankari, Salem – 637301
V. Sasikumar Department of Pharmaceutical Analysis, SS Institute of Pharmacy, Sankari, Salem – 637301
T. Sampathkumar Department of Pharmacognosy, SS Institute of Pharmacy, Sankari, Salem – 637301

Keywords:

Atorvastatin, Telmisartan, Metformin, High Fat Diet

Abstract

Objectives: To study the anti-obesity activity of telmisartan, atorvastatin and metformin alone and combination on high fat induced obesity in albino Wistar rats.

Materials and methods: Animals were divided into six different groups each comprising three animals. Group 1 (saline control), Group 2 (High fat diet), Group 3 (high fat diet + Atorvastatin), Group 4 (high fat diet + Telmisartan), Group 5 (high fat diet + Metformin), Group 6 (high fat diet + Atorvastatin + telmisartan + metformin).

Results: telmisartan, atorvastatin and metformin alone and combination shows anti-obesity activity on high fat diet induced obesity in albino Wister rats.

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Published

2021-09-01

How to Cite

C. Jothimanivannan, M. Vanitha, V. Sasikumar, & T. Sampathkumar. (2021). Comparative study of atorvastatin, metformin and telmisartan on high fat induced obesity in Albino Wistar rats: DOI: https://doi.org/10.54037/WJPS.2021.9905. World Journal of Pharmaceutical Sciences, 9(9), 181–186. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/49