Review on solid dispersion for suitable drug

DOI: https://doi.org/10.54037/WJPS.2021.9911

Abstract

Solubility is the phenomenon of dissolution of solute in solvent to give a homogeneous system is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired pharmacological response. There are many solubility techniques solid dispersion is one of the most important method for enhancing solubility of water insoluble drug. Solid dispersion is an effective way of improving the dissolution rate of poorly water-soluble drugs and hence its bioavailability. The water-soluble carriers used in preparation of solid dispersion enhance the dissolution rate of the poorly water-soluble drug. The review article focuses on the materials and methods of preparation, advantages, disadvantages and characterization of the solid dispersion.