Antiproliferative and Antioxidant potential of different extracts of Fritillaria roylei

Wajaht A. Shah; Tufeel Amin Mir; Ajaz Ahmed

Antiproliferative and Antioxidant potential of different extracts of Fritillaria roylei

Authors

Wajaht A. Shah Department of Chemistry, University of Kashmir, Hazratbal Srinagar, India-190006
Tufeel Amin Mir Department of Chemistry, University of Kashmir, Hazratbal Srinagar, India-190006
Ajaz Ahmed Department of Chemistry, University of Kashmir, Hazratbal Srinagar, India-190006

Keywords:

Fritillaria roylei; cytotoxic; antioxidant

Abstract

Fritillaria roylei is one of the medicinal plant used in traditional system of medicine for ailment of various diseases. But scientific study of the plant has been less carried out for which the study was conducted for validation of prevailing medical practice. The soxhlet extraction of the plant were conducted in various solvents (hexane, chloroform, ethyl acetate, methanol and water) differing in polarity. The phytochemical screening of extracts revealed the presence of alkaloids, saponins and tanins. In vitro Cytotoxicity evaluation against five human cancer cell lines A549 (Lung), C6 (Glioma), T47D (Breast), MCF (Breast), and TH-1(Colon) showed that the extracts of Fritillaria roylei exhibited potent cytotoxic activity. The extracts of Fritillaria roylei also showed antioxidant activity.

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Published

2014-04-01

How to Cite

Wajaht A. Shah, Tufeel Amin Mir, & Ajaz Ahmed. (2014). Antiproliferative and Antioxidant potential of different extracts of Fritillaria roylei. World Journal of Pharmaceutical Sciences, 2(4), 386–389. Retrieved from https://wjpsonline.com/index.php/wjps/article/view/antiproliferative-antioxidant-potential-fritillaria-roylei