Anthelmintic Activity of Hydroalcoholic Extract of Leaves of Valeriana Jatamansi
Keywords:
Valeriana jatamansi, Phytochemical Screening, Earthworm, Roundworm and AntihelminticAbstract
The hydroalcoholic extract of leaves of Valeriana jatamansi was investigated for anthelmintic activity using adult earthworms (Pheretima posthuma) and roundworms (Ascaridia galli). Various concentrations (100, 200, 400 mg/ml) of plant extract were used in the present study. Albendazole (10 mg/ml) was used as reference standard drug. Paralysis time and death time of the worms were recorded to assess the anthelmintic activity. Anthelmintic activity was noted at all the concentration (100, 200, 400 mg/ml). However, the hydroalcoholic extract exhibited anthelmintic activity at highest concentration of 400 mg/ml for both the worms. The result shows that hydroalcoholic extract possesses wormicidal activity and found to be effective as an anthelmintic may be due to presence of phenols as revealed in the phytochemical screening.
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