Evaluation of anti-arthritic potential of NONI extract in experimental rats

Abstract

Morinda citrifolia popularly known as Noni, is well known for its medicinal properties in folk medicine. The methanolic fruit extract of Noni was evaluated for anti-arthritic activity in rats by Complete Freund’s adjuvant method using Glucosamine sulphate (300 mg/kg) as the standard drug. The parameters such as paw volume, body weight, copper level and hematological parameters was determined and histopathological studies was carried out to assess the effect of extract on joints of the hind paw. Immunological parameters were estimated to determine the level of C-reactive protein. Results showed significant anti-arthritic activity of Noni extract in experimental rat model.