Antimicrobial Activity of some quinazoline heterocycles

Abstract

Derivatives of Quinazoline heterocycles possess a broad spectrum of pharmacological action. This class of compounds is known to be subjected to a large variety of structural modifications in order to synthesize derivatives with different biological properties. A series of new Quinazoline heterocycles are synthesized from chalcone. The characterization was done by IR, NMR and mass spectral data. The screening of antimicrobial activity of these synthesized compounds were done in vitro against some four Gram positive and four Gram negative strains of bacteria as well as four fungal strains in Dimethylformamide.