Chemical investigation and isolation of some constituents from Paralemnalia thyrsoides

Abstract

Soft coral constituents are an important group of marine’s invertebrates widely distributed in the coral reefs of the world ocean and have proven to be a biochemical warehouse for terpenes of them, examples of these soft corals are the animals belonging to genus paralemnalia. The organism of Paralemnalia thyrsoides was frozen immediately after collection and the freeze-dried organism was extracted sequentially with EtOAc. Phytochemical investigation of Egyptian octocoral Paralemnalia thyrsoides lead to the isolation of two compounds were identified as lemnolin A and gorgostane. Their structures were identified using 1D & 2D-NMR spectra and by comparison with data reported in the literature. The isolated compounds were evaluated for their antifungal activity against (Aspergillus fumigatus and Candida albicans) and antibacterial activity against (gram positive bacteria Staphylococcus aureus) and (gram-negative bacteria Escherichia coli), they showed week inhibitory activity.