Stability Indicating RP-HPLC Method for Simultaneous Estimation Of Remogliflozin And Teneligliptin

Abstract

A straightforward, accurate, and exact technique for estimating Remogliflozin and Teneligliptin in pharmaceutical dose form was devised. The chromatogram was done via an Ascentis 150 x 4.6 mm, 5m column. 0.01N Kh2:30 is present in the mobile phase. Acetonitrile in the 70:30 ratio was pushed through the column at a flow rate of 1.0ml/min. The retention time of Remogliflozin and Teneligliptin was determined to be 2.271 minutes and 2.706 percent RSD of Remogliflozin and Teneligliptin were found to be 0.6 and 0.5, respectively. %Remogliflozin and Teneligliptin recovered at 99.73% and 99.63%, respectively. The LOD and LOQ values derived from Remogliflozin and Teneligliptin regression models were 0.01, 0.04 and 0.48, 1.47, respectively. Teneligliptin's regression equation is y 40715x + 60.86, whereas Remogliflozin's is y = 16468x + 2301. Retention periods